WIT Press


Manufacture And Morphological Characterization Of Osteoconductive Porous Scaflolds

Price

Free (open access)

Paper DOI

10.2495/MC030051

Volume

43

Pages

10

Published

2003

Size

807.60 kb

Author(s)

A. Mazzoli, G. Moriconi, 0. Favoni & A. Mammoli

Abstract

Manufacture and morphological characterization of osteoconductive porous scaffolds A. Mazzoli ', G. Moriconi ', 0. Favoni ' & A. Mammoli I Department of Materials and Environment Physics and Engineering, Marche Polytechnic University, Ancona (Italy). 2 Department of Mechanical Engineering, University of New Mexico, Albuquerque (USA). Abstract This paper discusses the manufacturing, chemical, and physical characterization of a three-dimensional porous scaffold developed for the repair of skeletal defects. Autografts from patient donor sites are the current gold standard. However donor sites morbidity and a limited material supply restrict this treatment option. This is the main reason why the presence of synthetic biomaterials has grown significantly over the past two decades with applications in orthopedics. Bone consists of cortical and spongy regions both composed of Gas,? (PO4)4,3 (HP04, C03)1,7 (OH,C03)0,3 mineral phase. Spongy bone is a highly spongy tissue (55-70% interconnected porosit

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