Author(s)

B. Filipič & J. Štrancar

Abstract

Advanced parameter optimization in EPR spectroscopy B. ~ i l i ~ i ~ ' & J. &rancar2 ' ~ e ~ t . of Intelligent Systems, Joief Stefan Institute, Ljubljana, Slovenia 2 Dept. of Solid State Physics, Joief Stefan Institute, Ljubljana, Slovenia Abstract We present an automated optimization procedure to enhance the characterization of biological systems with electron paramagnetic resonance (EPR). EPR is a physical phenomenon exploited in EPR spectroscopy to detect changes in organisms caused by biologically active substances or resulting from pathological conditions. In the past, EPR spectral characteristics were interpreted manually, while nowadays numerical spectrum simulation makes it possible to obtain more reliable and biologically meaningful information about the inspected system. For this purpose, the parameters of the spectrum simulation model need to be tuned so that the resulting simulated spectrum matches with the experimentally obtained EPR spectrum. To search for appropriate parameter v

Keywords