WIT Press


Application Of PIV And PTV Techniques To Study Propensity For Thrombogenesis In PHV

Price

Free (open access)

Paper DOI

10.2495/BIO030251

Volume

6

Pages

10

Published

2003

Size

429.95 kb

Author(s)

M. Grigioni, C. Daniele, A. Balducci, G. /Avenio, G. Querzoli, G. P. Romano & V. Barbaro

Abstract

Application of PIV and PTV techniques to study propensity for thrombogenesis in PHV M. ~ r i ~ i o n i l , C. ~ a n i e l e ' , A. ~alduccil, ~ ' ~ v e n i o ' , G. ~uerzoli', G.P. ~ o r n a n o ~ , Barbaro v.' i Laboratov of Biomedical Engineering, Istituto Superiore di Sanita, Rome, Italy '~e~artement of ~ngineering for the Territory, University of Cagliari, Cagliwi, Italy j~e~artment of Mechanics and Aeronautics, University of Rome "La Sapienza ': Rome, Italy Abstract The evaluation of the performances of a prosthetic heart valve (PHV) is related to the efficiency in replacing the diseased native valve. However, critical aspects remain in the post-implantation stage, due to the damage on red blood cells when the induced mechanical stresses overcome a certain threshold; furthermore, undesired effects of platelets adhesion and activation could take place due to high residence times. The purpose of this study is to show how to obtain information about residence times downstream of a PHV by mea

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