Author(s)

R.F. Kunz, D.C. Haworth, L.S. Leemhuis, A.C. Davison, S. Zidowitz & A. Kriete

Abstract

Eulerian multiphase CFD analysis of particle transport and deposition in the human R.F. ~ u n z ' , D.C. ~aworth', L.S. ~eemhuis', A.C. ~avison', S. zidowitz2 & A. K.riete3 I Applied Research Laboratory, The Pennsylvania State University, University Park, PA, USA 'center for Medical Diagnostic Systems and Visualization, Universitaetsallee 29, Bremen, Germany. 3 Image Processing Laboratory, Institute of Anatomy and Cell Biology, Aulweg 123, Giessen, Germany Abstract The authors' recent research in the application of three-dimensional, multiphase Computational Fluid Dynamics (CFD) analysis of particle transport and deposition in the human lung is summarized in this paper. A physically accurate representation of the trachea and upper bronchi generations are obtained using high-resolution computed tomography (HRCT) of a rubber cast of an adult human tracheobronchial tree. A computer model of this data is used as a bounding surface for a hybrid unstructured CFD mesh. The differential model employ

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