WIT Press

Effects Of Tumour-induced Flow Patterns On Aerosol Drug Delivery

Price

Free (open access)

Paper DOI

10.2495/BIO970131

Volume

4

Pages

10

Published

1997

Size

813 kb

Author(s)

X. Guan & T.B. Martonen

Abstract

This manuscript presents a theoretical study of fluid dynamics in diseased lungs. The objective was to describe fluid behavior and assist in the development of new techniques for targeted delivery of drugs. Numerical simulations were conducted using FIDAP on the Cray T90 supercomputer. Two lung bifurcations with tumors in tracheobronchial airways were considered. Weibel [1] lung morphology and Hofmann et al. [2] breathing parameters were employed. It has been observed that the effects of tumor size, rat

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