WIT Press

Three-Dimensional Optimization Of Arterial Tree Models

Price

Free (open access)

Paper DOI

10.2495/BIO970011

Volume

4

Pages

10

Published

1997

Size

1,057 kb

Author(s)

R. Karch, W. Schreiner, M. Neumann & F. Neumann

Abstract

The computational method of Constrained Constructive Optimization has been gener- alized to grow arterial model trees within a three-dimensional perfusion volume, repre- senting a piece of tissue to be supplied with blood. Starting from an inlet at the surface of the perfusion volume, a binary branching tree of cylindrical tubes is generated so as to fulfill several physiologic boundary conditions and constraints. The model tree is grown by successively adding terminal segments while optimizing the geometric loca- tion and topological site of each new connection according to minimum total intravasal volume. Introducing additional "post-optimization" steps into the optimizat

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