Author(s)

R.W.G. Cloutman

Abstract

A mathematical model of the human renal system is presented within the context of a simulated clinical environment. The overall model contains a number of interrelated physiological subsystem models to represent hormonal and cardiovascular control and regulation of renal action for both water and electrolyte distribution. Control equations for each subsystem are solved numerically using VisSim, a powerful and easy to use Windows- based block-diagram language for system simulation. This simulation tool allows parameters to be varied as the simulation progresses which enables hypotheses to be investigated dynamically. The computer-based renal model is incorporated into a simulated clinical environment using the add-on utility VisSim-RT which provides an interface to custom built hardware

Keywords