Author(s)

A. Urbaszek, H. Hutted & M. Schaldach

Abstract

Simulation of the cardiovascular mechanics during rate adaptive pacing A. Urbaszek", H. Hutted & M. Schaldach" "Zentralinstitut fur Biomedizinische Technik, Universitdt Erlangen-Nurnberg, Turnstrafle 5, D-91054 Erlangen, Germany ^Institut fur Elektro-und Biomed. Technik, Universitdt Graz, Infeldgasse 18, A-8010 Graz, Austria ABSTRACT A numerical model of the human cardiovascular system will be presented that was developed for simulating the short-term regulatory processes that adapt the cardiac output of the heart to changing circulatory demands. Both normal and pathological states, e.g. sick sinus or AV block, are considered. The purpose of the simulations is to investigate the control aspects of rate responsive pacing and to develop and test algorithms for rate adaptation based on cardiac control signals. INTRODUCTION Today's multiprogrammable pacemakers provide patients with improved cardiac function by correcting bradydardic dysarrhythmias and res

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