WIT Press


Blood Damage Measures For Ventricular Assist Device Modeling

Price

Free (open access)

Paper DOI

10.2495/MB030131

Volume

36

Pages

10

Published

2003

Size

470 kb

Author(s)

D. Arora, M. Behr & M. Pasquali

Abstract

Blood damage measures for ventricular assist device modeling D. ~rora', M. ~ e h r ' & M. pasquali2 'Department of Mechanical Engineering and Materials Science, MS321, Rice University, 661 00 Main Street, Houston, TX 77005, USA 2~epartment of Chemical Engineering, MS362, Rice University, 6100 Main Street, Houston, 7X 77005, USA Abstract The development of implantable ventricular assist devices-in particular, continuous- flow axial and centrifugal pumps-offers hope to many heart attack victims waiting for donor hearts. These autonomous devices are intended as a medium- term bridge to transplant, or, if enough progress is made, even as a permanent clinical solution. One challenge that needs to be addressed in the design phase of blood pumps is the elevated level of shear stress, and the hemolysis response of the red blood cells, which depends on both the dose and time of exposure. The distribution of the shear stress levels in a complex flow field of a rotary blood pump chamber, as well as the m

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