Author(s)

R.T. Hart

Abstract

The observations and ideas behind current thinking and simulation of the functional adaptation of bone are presented. Several phenomenological models and mechanistic models are summarized. In addition, the use of computational implementations for some of the theoretical notions is briefly introduced. Introduction The adaptation of bone shape to its mechanical usage has been a topic of considerable recent interest. First, the relationship between bone form and function raises questions of basic physiological interest. Additionally, advances in understanding bone's adaptation to mechanical use are expected to result in specific strategies to improve the design and success of implanted endoprostheses, and to improve clinical treatment of specific bone disorders. It has been known since at least Gallileo's time [14] that bone's form is bas

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