WIT Press

The Development Of 3D Simulation Models To Represent Tumour Growth

Price

Free (open access)

Paper DOI

10.2495/BIO950051

Volume

2

Pages

8

Published

1995

Size

789 kb

Author(s)

C. Blackburn, L. Dunckley & G.A. Davies

Abstract

The computer modelling of cell proliferation is becoming important in a number of medical, biological and biotechnological applications. This research adopts an entirely new way of looking at cellular systems, using a model in 3D tessellated space defined in polyhedra based on the algorithm of Bowyer. This is combined with a discrete event simulation which includes normal cell division, characterised by a shorter mean division time, cell death and cell removal. Data gathered from the model is based on 3D Voronoi tessellations. The growth of tumour cells depends on the rate of mitosis and the cell cycle time. The stochastic model will include these factors, to provide information on growth rates, blood supply and the

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