WIT Press

Biomedical Application Of The Supercomputer: Targeted Delivery Of Inhaled Pharmaceuticals In Diseased Lungs

Price

Free (open access)

Paper DOI

10.2495/BIO950291

Volume

2

Pages

8

Published

1995

Size

585 kb

Author(s)

T.B. Martonen, I. Katz, D. Hwang & Y. Yang

Abstract

The primary pathological manifestation of cystic fibrosis (CF) is the ob- struction of biological passages throughout the body by mucus. However, all patients will develop chronic obstructive lung disease which accounts for more than 90% of CF mortality. We have used the Cray Y-MP to develop a mathematical model for targeting the delivery of inhaled pharmacologic drugs in the treatment of respir

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