WIT Press

A Mathematical Model Of The Interaction Between Arterial And Cardiopulmonary Baroreceptors During Acute Cardiovascular Stress

Price

Free (open access)

Paper DOI

10.2495/BIO950171

Volume

2

Pages

8

Published

1995

Size

791 kb

Author(s)

M. Ursino

Abstract

A mathematical model of some mechanisms involved in the short term arterial pressure control is described. The model considers two main baroreceptor systems (arterial and cardiopulmonary), the pressure-volume characteristics of the systemic and pulmonary circulations, their hydraulic resistances, and the dependence of cardiac output on afterload and preload. In this work, the possible role of cardiopulmonary baroreceptors, and their interaction with the arterial baroreceptors is investigated during mild haemorrhage or lower body negative pressure (LBNP). Model simulations suggest that the cardiopulmonary baroreflex control acting on systemic resistance and venous unstressed volume plays a pivotal role in buffering mild changes in blo

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